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Tuberculosis

Tuberculosis, or TB, is an infectious disease that is treated with antibiotics. But some bacteria have found ways to resist or fight off the drug due to incorrectly administered treatment. When the two main antibiotics stop being effective against the disease, it is labeled multi-drug resistant tuberculosis, or MDR-TB. MDR-TB is a real killer, and a major public health issue, but for the...
"The arduous journey towards being cured of drug-resistant tuberculosis (DR-TB) requires tremendous personal strength" writes Lynee Wilkinson, MSF project coordinator in Khayelitsha, Cape Town... Medication for regular TB is now available at most public health clinics, but many people travel to hospitals far away and the support structures they so desperately need to help them stay on course to...
Treating patients with multidrug-resistant (MDR) tuberculosis (TB) at their local clinics improves access to care and costs 40% less than confining them to hospital, according to a report by Medicins Sans Frontières published on Tuesday to coincide with World TB day... "Drug-resistant TB is a public health emergency and we need to throw all we have at it. We are in big trouble,"Medicins Sans...
The buzz started well before the first new TB drug in half a century was approved for use on the last day of 2012: two forthcoming new TB medicines would radically improve cure and survival rates for drug-resistant tuberculosis (DR-TB), displacing the toxic and grueling multi-year treatments that, even with only a 50% chance of cure, were the only options available. As an organisation...
  The first new TB drugs in decades have received conditional regulatory approval, but remain largely out of the reach of patients. Re-purposed medicines are showing effectiveness against TB, but aren't registered for that purpose, which hinders their use in treating TB patients. High prices are another significant barrier to accessing promising new and...
Since 2007, in response to the growing epidemic of drug-resistant tuberculosis (DR-TB) in Khayelitsha, Doctors Without Borders (MSF), City of Cape Town and the Western Cape Departments of Health have been piloting a decentralised model of care for DR-TB patients. Khayelitsha is a township with one of the highest burdens of HIV infection and tuberculosis across South Africa and globally....
LESS THAN 20% of the estimated number of multidrug-resistant tuberculosis (MDR-TB) emerging each year worldwide are diagnosed as such, and an even smaller percentage receive appropriate secondline treatment. The cost of MDR-TB treatment is a major barrier to treatment scale-up in many settings, with MDR-TB treatment estimated to cost around 26 times more than...
Doctors Without Borders (MSF) and Research Center in Borstel, Germany publish findings in New England Journal of Medicine. Swaziland - More than a quarter of multi-drug resistant tuberculosis (MDR-TB) strains isolated in a national survey in Swaziland carry a mutation that is undetectable by the advanced rapid molecular diagnostic tests currently in widespread use, according to a letter...
A medical forum in Armenia gathers health authorities and specialists to discuss tuberculosis, one of the main public health issues in the region. New drugs and therapeutic approaches give hope of better treatment outcomes. Joint and renewed efforts are needed to obtain a better access to the most effective drugs and new treatment regimens for the resistant form of the disease. Yerevan / Paris...
As fighting in eastern Ukraine continues to escalate, Doctors Without Borders (MSF) urges all parties to the conflict to halt shelling of hospitals and ensure civilians can reach safe places. In response to the surge in violence over the last two weeks, the organization is urgently expanding its support to hospitals on both sides of the frontline as continued heavy fighting traps civilians...
With continued fighting in the Donetsk region in eastern Ukraine, MSF is providing medical supplies, including dressings, bandages, syringes, antibiotics and stretchers, to hospitals in the region. MSF has been working in Donetsk since 2011, running a program to treat patients with drug-resistant tuberculosis within the regional penitentiary system. Since March 2014, MSF has also been...
  Introduction Drug resistant tuberculosis (DR TB) patient support models of care were designed and piloted by MSF OCB Khayelitsha project in response to the need for a structured approach to the treatment literacy and counseling offered to patients diagnosed with DR TB. This training module should be read and used by trainers to design DR TB patient support...
Drug-resistant tuberculosis (DR-TB) robbed 24-year-old Phumeza Tisile, a former Doctors Without Borders (MSF) patient of her hearing... Now, she is fighting to get it back through a national fundraising campaign, but time is running out. Read article HERE
  In Zimbabwe’s many places people still live a rural life with their cattle and goats, existing from what they cultivate. Big clinics are far away. For those living with HIV who need their antiretroviral therapy (ART) regularly this may cause big problems. To bring the drugs to the patients, in 2012 Doctors without Borders (MSF) started decentralising...
In their quest to gain the much needed support countrywide, Doctors Without Borders South Africa/ Medecins Sans Frontieres (MSF) representatives Prince Moalafi and Bongolethu Maqungo undertook a fundraising campaign at The Boardwalk Inkwazi Shopping Centre last week... The dynamic duo took to the centre's busy passages to persuade festive shoppers to sign up and support the humanitarian...
  72% of stock outs of 53 drugs unresolved – Stop Stock Outs Project demands urgent action plan to avert crisis for thousands of patients JOHANNESBURG – The Stop Stock Outs Project (SSP) calls for immediate action by Gauteng Health MEC Qedani Mahlangu to avert crisis for thousands of patients as a spike in unaddressed medicine stock outs at public healthcare...
With winter settling in in eastern Ukraine, Doctors Without Borders (MSF) is continuing its support to hospitals on both sides of the frontline, and expanding its psychological assistance to help people living in some of the hardest hit areas. Despite the signing of a ceasefire agreement on 5 September, fighting has continued in several cities and towns, with particularly heavy clashes taking...
Andaleeb Rinquest remembers the moment she accepted, with certainty, the imminence of her own death... Lying in a state hospital ward for extensively drug resistant tuberculosis (XDR TB) patients, in the painful final throes of the disease, she looked to her left... There her friend Jolene, similarly weak and skeletal, lay... Jolene’s family were too poor to travel 50 kilometres from...
Pretoria, 30 October - Three drug-resistant tuberculosis (DR-TB) patients-turned-activists, including Phumeza Tisile, Andaleeb Rinquest and Morgan Scholtz will be joined by health advocates in handing over a letter to the Registrar of Medicines signed by over 100 clinicians, organisations and patients with DR-TB. The letter demands the immediate registration of a generic version of linezolid,...
South Africa’s AIDS epidemic is at its worst in high-risk subgroups like gay men, prostitutes, truckers, prisoners, miners and patients who don’t take their drugs regularly... To have any hope of beating the epidemic, it must focus on such groups, experts say... Many pilot projects to do that have been started among them the Sex Workers Project, the Ndlovu Care Group and the Doctors...
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