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Tuberculosis

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  In settings with a high HIV/TB burden and significant shortages of human resources for health (HRH), task shifting strategies have relied on lay workers to provide HIV testing and counselling (HTC) and adherence support for HIV and TB treatments. While in some countries these tasks were integrated into the work of existing community cadres such as...
Doctors Without Borders (MSF) says a new combination of drugs created to treat extensively drug-resistant TB (XDR-TB) is having a significant impact on a group of patients who are in the midst of a two-year treatment to cure their disease. In 2013, an MSF team in Grozny noticed that a growing number of patients with multi-drug resistant TB (MDR-TB) were not responding to second-line...
An MSF patient in Russia describes the physical and mental anguish of suffering from XDR-TB     Elena is a 35-year old resident of Grozny, Chechen Republic, in the Russian Federation. MSF diagnosed her with extensively drug-resistant tuberculosis (XDR-TB) in December 2013. Due to an absence of drugs for this form of tuberculosis, she was put on standard...
With more than one in 10 health facilities nationally reporting a drug stock out in the last nine months, this year’s SA AIDS Conference may have been more about what’s missing than what’s been done in the country’s HIV programme... Research into medicine shortages by the civil society coalition Stop the Stock Outs Project cast a long shadow over this year’s national AIDS...
  One of the biggest frustrations faced by rural clinicians at the coalface of healthcare delivery in clinics and district hospitals is that short, yet devastating sentence: “Sorry, it’s out of stock”. It is hard to describe the helplessness and anger one feels when cheap, yet important medications such as anti-hypertensives, anti-...
Stop Stock Outs Project releases second annual survey indicating persistent medicine shortages in majority of provinces and calls for an emergency response   DURBAN – Chronic shortages of essential medicines, including antiretroviral (ARVs), tuberculosis, vaccines and other medicines, in health facilities across South Africa require urgent, sustained and co-ordinated action from...
Drug-resistant tuberculosis is a major health challenge across much of Africa, but a new medicine being pioneered in South Africa could be a breakthrough after decades of frustration... Bedaquiline is being made available to 3 000 people suffering side effects of the usual drug-resistant tuberculosis treatment, or who have developed complete drug resistance...  Dr Jennifer Hughes,...
Tuberculosis, or TB, is an infectious disease that is treated with antibiotics. But some bacteria have found ways to resist or fight off the drug due to incorrectly administered treatment. When the two main antibiotics stop being effective against the disease, it is labeled multi-drug resistant tuberculosis, or MDR-TB. MDR-TB is a real killer, and a major public health issue, but for the...
"The arduous journey towards being cured of drug-resistant tuberculosis (DR-TB) requires tremendous personal strength" writes Lynee Wilkinson, MSF project coordinator in Khayelitsha, Cape Town... Medication for regular TB is now available at most public health clinics, but many people travel to hospitals far away and the support structures they so desperately need to help them stay on course to...
Treating patients with multidrug-resistant (MDR) tuberculosis (TB) at their local clinics improves access to care and costs 40% less than confining them to hospital, according to a report by Medicins Sans Frontières published on Tuesday to coincide with World TB day... "Drug-resistant TB is a public health emergency and we need to throw all we have at it. We are in big trouble,"Medicins Sans...
The buzz started well before the first new TB drug in half a century was approved for use on the last day of 2012: two forthcoming new TB medicines would radically improve cure and survival rates for drug-resistant tuberculosis (DR-TB), displacing the toxic and grueling multi-year treatments that, even with only a 50% chance of cure, were the only options available. As an organisation...
  The first new TB drugs in decades have received conditional regulatory approval, but remain largely out of the reach of patients. Re-purposed medicines are showing effectiveness against TB, but aren't registered for that purpose, which hinders their use in treating TB patients. High prices are another significant barrier to accessing promising new and...
Since 2007, in response to the growing epidemic of drug-resistant tuberculosis (DR-TB) in Khayelitsha, Doctors Without Borders (MSF), City of Cape Town and the Western Cape Departments of Health have been piloting a decentralised model of care for DR-TB patients. Khayelitsha is a township with one of the highest burdens of HIV infection and tuberculosis across South Africa and globally....
LESS THAN 20% of the estimated number of multidrug-resistant tuberculosis (MDR-TB) emerging each year worldwide are diagnosed as such, and an even smaller percentage receive appropriate secondline treatment. The cost of MDR-TB treatment is a major barrier to treatment scale-up in many settings, with MDR-TB treatment estimated to cost around 26 times more than...
Doctors Without Borders (MSF) and Research Center in Borstel, Germany publish findings in New England Journal of Medicine. Swaziland - More than a quarter of multi-drug resistant tuberculosis (MDR-TB) strains isolated in a national survey in Swaziland carry a mutation that is undetectable by the advanced rapid molecular diagnostic tests currently in widespread use, according to a letter...
A medical forum in Armenia gathers health authorities and specialists to discuss tuberculosis, one of the main public health issues in the region. New drugs and therapeutic approaches give hope of better treatment outcomes. Joint and renewed efforts are needed to obtain a better access to the most effective drugs and new treatment regimens for the resistant form of the disease. Yerevan / Paris...
As fighting in eastern Ukraine continues to escalate, Doctors Without Borders (MSF) urges all parties to the conflict to halt shelling of hospitals and ensure civilians can reach safe places. In response to the surge in violence over the last two weeks, the organization is urgently expanding its support to hospitals on both sides of the frontline as continued heavy fighting traps civilians...
With continued fighting in the Donetsk region in eastern Ukraine, MSF is providing medical supplies, including dressings, bandages, syringes, antibiotics and stretchers, to hospitals in the region. MSF has been working in Donetsk since 2011, running a program to treat patients with drug-resistant tuberculosis within the regional penitentiary system. Since March 2014, MSF has also been...
  Introduction Drug resistant tuberculosis (DR TB) patient support models of care were designed and piloted by MSF OCB Khayelitsha project in response to the need for a structured approach to the treatment literacy and counseling offered to patients diagnosed with DR TB. This training module should be read and used by trainers to design DR TB patient support...
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