South Africa’s AIDS epidemic is at its worst in high-risk subgroups like gay men, prostitutes, truckers, prisoners, miners and patients who don’t take their drugs regularly... To have any hope of beating the epidemic, it must focus on such groups, experts say... Many pilot projects to do that have been started among them the Sex Workers Project, the Ndlovu Care Group and the Doctors Without Borders' Ubuntu Clinic... South Africa’s first antiretroviral clinic is still breaking ground... Its “adherence clubs” have become a model for getting patients to keep taking their pills... In 1999, Doctors Without Borders joined forces with a clandestine operation run by AIDS activists in Khayelitsha, a black township outside Cape Town.

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