While clinical disease caused by drug-sensitive Mycobacterium tuberculosis (MTB) can usually be treated successfully, clinical disease caused by drug-insensitive MTB is associated with a poorer prognosis... In December 2012, a new drug, bedaquiline, was approved by the US Food and Drug Administration...This article documents the process whereby the National Department of Health, Right to Care and Doctors Without Borders obtained access to this medication for South Africans who might benefit from subsequent implementation of the Clinical Access to Bedaquiline Programme.  

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