Just days into the rollout of fixed-dose combination (FDC) antiretrovirals (ARVs) by South Africa’s HIV treatment programme - the world's largest - activists are raising fears of drug shortages...Motsoaledi launched the phased rollout of FDCs on 8 April at a small community health centre north of the country's capital, Pretoria. New patients and HIV-positive women who are pregnant or breastfeeding will be the first to receive the new medication...But stock shortages have already been reported in Western Cape Province and more are thought to be occurring in other provinces, according to activists. In March, the Western Cape Department of Health told AIDS lobby group the Treatment Action Campaign (TAC) and Doctors Without Borders (MSF) that it had received significantly smaller stocks of the FDCs than had been ordered from suppliers... Dr Lynne Wilkinson, the MSF project coordinator in Khayelitsha, a township on the outskirts of Cape Town, said this meant the depot could not maintain the usual two- or three-month buffer stock...

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