Doctors Without Borders, MSF activities in South Africa

South Africa

In South Africa, we respond to disease epidemics, non-communicable diseases, and assist migrants with access to healthcare.

In October 2023, in partnership with the Eastern Cape Department of Health, we launched a project to improve the identification and management of non-communicable diseases (NCDs) in the Amathole District, which is MSF's first NCD project in South Africa.  We aim to apply lessons from two decades of working on HIV and tuberculosis (TB) in South Africa to enhance NCD care in rural settings.

We also work with undocumented people and migrants in Tshwane, where we run a project that provides access to vaccines for these underserved communities.

Having achieved the UNAIDS 90-90-90 target in 2018 in Eshowe, KwaZulu-Natal, we redirected our approach to tackle the TB epidemic and reduce the number of cases in the area.

After 22 years of activities and campaigning, we closed our HIV and TB project in Khayelitsha, Western Cape in 2020.
 

Our activities in 2025 in South Africa

Data and information from the International Activity Report 2025.

MSF activities in South Africa in 2025 In South Africa, Doctors Without Borders (MSF) assisted foreign nationals physically blocked from accessing public health facilities by anti-migrant groups, while continuing to run a non-communicable diseases (NCDs) project in Butterworth.
MSF, Doctors Without Borders, MSF activities in South Africa in 2025

From July through September, anti-migrant groups camped outside dozens of clinics and hospitals in Gauteng, preventing foreign nationals, including pregnant women and people living with HIV, from seeking medical care.

Our teams refilled antiretroviral medication for people living with HIV who could not collect it themselves at the blocked health facilities, and we referred patients to alternative health facilities unaffected by blockages.

Throughout 2025, we continued to run an NCD project in Butterworth, Eastern Cape province, in partnership with the Department of Health. To strengthen skills for NCD management, we launched a side-by-side nurse mentorship and coaching programme across seven facilities, and classroom-based training for health professionals in 60 Department of Health facilities. In addition, to promote patient wellbeing, we piloted healthy lifestyle groups with two community-based organisations, focusing on educating members on nutrition, diet, and exercise. Participants were then encouraged to engage in healthy cooking and gardening activities, organised in collaboration with the Department of Agriculture.

After training health staff, we piloted the use of HbA1c blood testing for diabetes* in five of the seven facilities. In addition, we donated equipment and supplies for NCD management and diagnosis, such as digital blood pressure monitors, vital signs monitors, height and weight scales, and glucometers.

By the end of 2025, we had renovated and equipped an additional external pick-up point for medication, bringing the total number to four. Pick-up points provide reliable and accessible medicines for patients with chronic diseases. They are managed by trained community members, who distribute the medication free of charge to patients on behalf of the government. 

* This form of testing provides a longer-term understanding of glycaemic control, particularly for people who are pre-diabetic or living with Type 2 diabetes.

MSF'S MEDICAL ACTIVITIES IN 2025

 
Vials of Amphotericin B and related supplies which is used to treat Cryptococcal Meningitis  Aisha Diabate 30 years (background) arrived at Donka Hospital with the husband of her sister who is a doctor from Coleah health centre in Conakry.
HIV/Aids

Three considerations to treat or manage cryptococcal meningitis

Patient and Staff Stories 30 Nov 2021
 
MSf, Doctors Without Borders, South Africa, Word AIDS day, Cryptococcal meningitis
HIV/Aids

"I started having headaches, not just normal headaches… serious headaches. I couldn’t even sit or sleep."- Zikhona Mboto

Patient and Staff Stories 30 Nov 2021
 
With approximately 5.3 million people infected with HIV, South Africa has the highest number of people living with HIV/AIDS of any country. In November 2003, the South African government approved a new national HIV/AIDS plan that added life-extending antiretroviral (ARV) therapy to the existing protocol and set a goal of treating 600,000 people with ARVs by 2008.
HIV/Aids

Cryptococcal meningitis: This world AIDS Day it’s time to recognise an outsider

Op-Ed 30 Nov 2021
 
MSF, Doctors Without borders, HIV Drug CAB-LA
HIV/Aids

Deadly brain fungus is killing people living with HIV while SAHPRA dithers over registration of cure

Press Release 30 Nov 2021
 
A store room containing medications and care packages which are distributed to vulnerable populations around Johannesburg by fieldworkers working with MSF.
Coronavirus COVID-19 pandemic

Adopting TRIPS Waiver for unhindered access to COVID-19 medical tools more urgent

Press Release 26 Nov 2021
 
Switzerland, COVID-19 response in Intensive care unit of HUG. April 14, 2020.
Access to medicines

What's next for the world and South Africa?

Patient and Staff Stories 16 Nov 2021